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LUCAT1 knockdown suppresses clear cell renal cell carcinoma growth in vivo . (A) Tumor volume. (B) Images of tumors derived from Caki-1 cells stably transfected with sh-LUCAT1 <t>or</t> <t>sh-NC.</t> (C) Tumor weight. (D) The expression level of LUCAT1 was examined by reverse transcription-quantitative PCR. ** P<0.01. LUCAT1, lung cancer-associated transcript 1; sh, short hairpin, NC, negative control.
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LUCAT1 knockdown suppresses clear cell renal cell carcinoma growth in vivo . (A) Tumor volume. (B) Images of tumors derived from Caki-1 cells stably transfected with sh-LUCAT1 or sh-NC. (C) Tumor weight. (D) The expression level of LUCAT1 was examined by reverse transcription-quantitative PCR. ** P<0.01. LUCAT1, lung cancer-associated transcript 1; sh, short hairpin, NC, negative control.

Journal: Experimental and Therapeutic Medicine

Article Title: Long non-coding RNA LUCAT1 promotes the progression of clear cell renal cell carcinoma via the microRNA-375/YAP1 axis

doi: 10.3892/etm.2021.10186

Figure Lengend Snippet: LUCAT1 knockdown suppresses clear cell renal cell carcinoma growth in vivo . (A) Tumor volume. (B) Images of tumors derived from Caki-1 cells stably transfected with sh-LUCAT1 or sh-NC. (C) Tumor weight. (D) The expression level of LUCAT1 was examined by reverse transcription-quantitative PCR. ** P<0.01. LUCAT1, lung cancer-associated transcript 1; sh, short hairpin, NC, negative control.

Article Snippet: Lentiviral-based short hairpin (sh)-LUCAT1 vector and lentiviral empty vector (sh-NC) were obtained from Shanghai GeneChem Co., Ltd.

Techniques: In Vivo, Derivative Assay, Stable Transfection, Transfection, Expressing, Real-time Polymerase Chain Reaction, Negative Control